
Yeah, my initial REACTION is no.
The Big Bang Theory Season 2, Episode 22

in which I looked up
the REACTION rates
The Big Bang Theory Season 7, Episode 6

Leonard, what if you have
an allergic REACTION...
The Big Bang Theory Season 8, Episode 9

...or drinking coffee while driving
reduces one's REACTION time...
The Big Bang Theory Season 2, Episode 5

The REACTION has begun.
Breaking Bad Season 5, Episode 14